Kyle T. Howard, Ph.D.

Education

• Ph.D., Organic Chemistry, Syracuse University, 2016
• B.S., Chemistry, York College of Pennsylvania, 2010

Courses

• General Chemistry Lab
• Organic Chemistry Lab
• Perspectives of the Molecular World

Research Interests

• Organic synthesis and medicinal chemistry
• Synthesis and structure activity relationships studies of SHIP inhibitors
• Formation of PMB and DPM ethers using trichloroacetimidates under thermal conditions

Recent Publications

• Howard, K. T.; Duffy, B. C.; Linaburg, M. R.; Chisholm, J. D. "Formation of DPM ethers using O-diphenylmethyl trichloroacetimidate under thermal conditions." Org. Biomol. Chem. 2016, 14, 1623-1628. DOI: 10.1039/C5OB02455B
• Howard, K. T.; Chisholm, J. D. “Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis.” Org. Prep. Proced. Int., 2016, 48:1, 1-36. DOI: 10.1080/00304948.2016.1127096.
• Srivastava, N.; Iyer, S.; Sudan, R.; Youngs, C.; Engelman, R. W.; Howard, K. T.; Russo, C. M.; Chisholm, J. D.; Kerr, W. G. “SHIPi promotes an immunoregulatory milieu in adipose tissue to reverse age- and diet-  associated obesity and metabolic syndrome.” JCI Insight, 2016; 1(11).
• Fernandes, S.; Brooks, R.; Park, M-Y.; Srivastava, N.; Russo, C.M.; Howard, K.T.; Chisholm, J.D.; Kerr W.G. “SHIP Inhibition Enhances Murine Autologous and Allogeneic Hematolymphoid Cell Transplantation.” EBioMedicine, 2015, 2, 205-213. DOI:10.1016/j.ebiom.2015.02.004
• Duffy, B.C.; Howard, K. T.; Chisholm, J. D. “Alkylation of Thiols using Trichloroacetimidates under Neutral Conditions.” Tetrahedron Lett. 2015, 56, 3301-3305. DOI:10.1016/j.tetlet.2014.12.042

Service

• Chemistry Industry Advisory Council Liason