Faculty Bio

David Singleton, Ph.D.

Associate Professor of Biology


  • BA, University of Delaware (1987)
  • PhD, Case Western Reserve University (1992)


  • American Society for Microbiology
  • American Society for Cell Biology


  • BIO200, Introduction to Scientific Research
  • BIO216, Unseen Life
  • BIO230, Microbiology
  • BIO400, Senior Thesis

Research Interests

  • Assessment of antimicrobial efficacy
  • Metagenomics; isolation and characterization of environmental microorganisms
  • Cell biology of fungi
  • Use of yeast as a model for human diseases (Mad Cow Disease, cancer, metabolic errors)

Recent Publications

  • Dhillon, J, and D. Singleton. 2011. Prion propagation in response to temperature and osmotic stress. J Penn Acad Sci 84
  • Singleton, D. R., W. Kreiger, and J. Kreiger. 2010. Preliminary analysis of a megacryometeor recovered from an impact in York CountyOctober 2008. J Penn Acad Sci 83:144
  • Hazen, K.C., D.R. Singleton, and J. Masuoka. 2007. Influence of outer region mannosylphosphorylation on N-glycan formation by Candida albicans: Normal acid-stable N-glycan formation requires acid-labile mannosylphosphate addition. Glycobiology 17: 1052-1060
  • Singleton, D.R., P.L. Fidel, K.L. Wozniak, and K.C. Hazen. 2005. Contribution of cell surface hydrophobicity protein 1 (Csh1p) to virulence of hydrophobic Candida albicans serotype A cells. FEMS Microbiology Letters 244: 373-377